flor essence וסחוס כרישים

דיון מתוך פורום  טיפולים משלימים בסרטן

23/03/2007 | 01:39 | מאת: יעל

לד"ר ברנר שלום, האם אתה מכיר את flor essence והשפעתו על הסרטן? ומה לגבי סחו כרישים ? בתודה

לקריאה נוספת והעמקה

ליעל פלור אסנס היא תרכובת של 8 צמחי מרפא. 4 מהם הם המרכיבים של תרכובת אינדיאנית בשם ESSIAC שמצאה אחות קנדית בשם CAISSE (אסיאק זה ההיפוך של שמה). הפלור אסנס הוא פיתוח של האסיאק ואמור להיות יותר יעיל. יש הרבה דיווחים על יעילות בטיפול בסרטן אך אין מחקרים. מהניסיון האישי שלי בטיפול עם חומרים אלה בחולי סרטן, הם יעילים כחלק מטיפול כולל, יש להם יכולת לשפר את התפקוד של מערכת החיסון והם יעילים מאד בטיפול בתופעות לוואי של כימותרפיה, ובעיקר מונעים מוקוזיטיס ופגיעה בכדוריות הדם על ידי חומר כימותרפי בשם 5FU. סחוס כרישים הוא חומר אנטיאנגיוגנטית שפיתח מדען אמריקאי בשם ליין. הוא שם לב שלכרישים אין סרטן ומצא שהחומר האנטיסרטני נמצא בסחוס שלהם. זהו החומר הראשון הפועל בצורה אנטיאנגיוגני-כלומר מונע מהגידולים לפתח כלי דם חדשים הנחוצים להם כדי לגדול. רק כ 10 שנים לאחר הופעת הסחוס כרישים יצאו לשוק תכשירים אנטיאנגיוגנים קונבנציונליים כמו האבסטין. סחוס כרישים נמצא יעיל במחקרים בגידולי כליה וה FDA האמריקאי מכיר בתרופה זו כ"תרופה יתומה" במחלה זו. היצרן הגדול של תרופה זו היא חברת אטרנה מקנדה. ד"ר יוסף ברנר

23/03/2007 | 13:44 | מאת: עדיף גפילטע פיש

http://www.nrg.co.il/online/15/ART/834/707.html ******************************************************************* 1: Cancer. 2005 Jul 1;104(1):176-82. Evaluation of shark cartilage in patients with advanced cancer: a North Central Cancer Treatment Group trial. BACKGROUND: Shark cartilage has been a popular complementary OR alternative medicine intervention. The basis for this popularity is the claim that sharks rarely get cancer because of the high proportion of cartilage in the shark's body. However, early studies were equivocal. Therefore, a clinical trial was conducted to look at the impact of shark cartilage in patients with advanced cancer. The primary goal of this trial was to determine whether a shark cartilage product improved overall survival for patients with advanced cancer who were getting standard care. Secondary research goals were to evaluate toxicities, tolerability, AND quality of life associated with this shark cartilage product. METHODS: The study was a two-arm, randomized, placebo-controlled, double-blind, clinical trial. Patients with incurable breast OR colorectal carcinoma had to have good performance status AND organ function. Patients could be receiving chemotherapy. Patients were all to receive standard care AND then to be randomly selected to receive either a shark cartilage product OR an identical-appearing AND smelling placebo 3 to 4 times each day. RESULTS: Data on a total of 83 evaluable patients were analyzed. There was no difference in overall survival between patients receiving standard care plus a shark cartilage product versus standard care plus placebo. Likewise, there was no suggestion of improvement in quality of life for patients receiving the shark cartilage, compared with those receiving placebo. CONCLUSION: This trial was unable to demonstrate any suggestion of efficacy for this shark cartilage product in patients with advanced cancer. ************************************************************************************* JNCI Journal of the National Cancer Institute 2005 97(21):1562-1563; Sharks Do Get Cancer: Few Surprises in Cartilage Research Joel B. Finkelstein As is the case for many alternative remedies, dozens of shark cartilage products for a variety of medical conditions are already on the market despite a lack of strong clinical evidence to support their effectiveness. Although some laboratory studies have shown that shark cartilage may have antiangiogenic properties, it remains unclear whether future research will ultimately clarify troubling questions created by early human trials, some of which included a mixture of scientific conjecture AND product promotion. Folk remedies often carry the weight of convincing anecdotal experience, but the public interest in shark cartilage has been driven more by marketing than science, said Gary K. Ostrander, Ph.D., vice chancellor for research AND graduate education at the University of Hawaii at M noa. "People want to believe this stuff. They're desperate. They have limited time, limited resources," he said. For some, that belief came from a book published in 1992. In Sharks Don't Get Cancer, author William Lane, Ph.D., argued that the nearly nonexistent occurrence of solid tumors in sharks was because of cancer-fighting elements in their cartilage. "This is all based on the idea that sharks don't get cancer. Well, it turns out that sharks do get cancer," said Ostrander. He AND his colleagues cataloged findings of solid tumors in sharks in a review article, published in the Dec. 1, 2004, issue of Cancer Research, that also expounded on the dangers of pseudoscientific explanations for medical treatments. Once Lane's ideas came into the public, scientists began raising questions about the results of clinical studies he had conducted on cancer patients in Mexico AND Cuba. "None of the work was ever published in a peer-reviewed research journal, AND he was just playing with the artifacts," said Ostrander. It also later came to light that the shark cartilage product that Lane was studying, Benefin, was manufactured by Lane Labs, a company run by his son. In 1999, the U.S. Food AND Drug Administration pursued an injunction against the company for illegally promoting the product as a cancer treatment. And when Benefin was tested in a placebo-controlled trial, no benefit was found. "It wasn't well tolerated, there wasn't any suggestion of benefit in terms of quality of life, there wasn't any suggestion of benefit in terms of survival," said Charles L. Loprinzi, M.D., a cancer researcher at the Mayo Clinic in Rochester, Minn., who published the results of this study in the July 1 issue of the journal Cancer. "When we set out to do this as a placebo-controlled evaluation ... I would have loved to carry the banner of a positive study," said Loprinzi. But after his study's disappointing results, he is ready to move on. "We're not planning to look further at it, AND I wouldn't recommend anyone look further at the product we looked at," he said. Benefin is just one of many shark cartilage products already on the market. However, some of these are being developed more like pharmaceuticals. For example, AE-941, OR Neovastat, a standardized extract of shark cartilage, is currently being studied in a National Cancer Institute–sponsored phase III clinical trial for the treatment of non–small-cell lung cancer. Neovastat's manufacturer plans to seek U.S. Food AND Drug Administration approval for the drug. But comparing Neovastat AND Benefin is like comparing apples AND oranges, said Charles Lu, M.D., assistant professor at the University of Texas M. D. Anderson Cancer Center in Houston AND principal investigator for the NCI study. "The company has never made any money off of Neovastat," said Lu. "It is being treated as if it were an experimental drug." Federal law allows natural products such as Neovastat AND Benefin to be marketed as dietary supplements, although the companies cannot make specific disease claims for those products. Lane Labs, like many other companies, has taken advantage of that loophole to sell their remedies without clinical studies. Loprinzi said it is important to conduct clinical trials on these products so that the public can know the truth about whether they work. "It's appropriate for us to look at things that have a high profile that may not have as much scientific basis, but ... a lot of interest among the public," he said. The results of Loprinzi's study were not available when Natural Standard conducted their analysis, but his results aren't likely to improve shark cartilage's grade. Although there are other shark cartilage studies being planned, the evidence is already definitive enough for some people. "Do we need to do more [shark cartilage] clinical trials in people? I think the data is pretty clear that we don't," said Ostrander, who cites the findings of overseas studies in reaching that conclusion. "Everything that I have seen AND read suggests that there's never going to be an effective therapy using shark cartilage," he said. Ulbricht also noted that there were almost no data on the absorption AND bioavailability of shark cartilage products in humans.

23/03/2007 | 14:05 | מאת: FBI

http://www.cancer.gov/cancertopics/pdq/cam/cartilage/Patient/page2

23/03/2007 | 14:21 | מאת: TH1

אתה כותב: "מהניסיון האישי שלי בטיפול עם חומרים אלה בחולי סרטן, הם יעילים כחלק מטיפול כולל, יש להם יכולת לשפר את התפקוד של מערכת החיסון" . באיזה מבחנים IN VITRO או IN VIVO (בחולים) אתה בודק את תפקודי מערכת החיסון לאחר טיפול בתוספים? האם זה נבדק בקליניקה שלך? אפשר לקבל קצת תוצאות של לפני ואחרי ?

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