פולימיקרוגיריה

שלום. אפשר לדעת מה כתוב כאן? תודה. Clinical Manifestations of Polymicrogyria The clinical manifestations of polymicrogyria are stable neurologic deficits, i.e., a "static encephalopathy." •In the mildest form, polymicrogyria is unilateral with only one small region of the brain involved; d neurologic problems may not be evident. •In more severe forms, focal motor, sensory, visual, or cognitive problems may be present, depending on the location of the brain region affected. •In the most severe forms, polymicrogyria is bilateral and generalized, resulting in severe intellectual disability, cerebral palsy, and refractory epilepsy. Regression of development or loss of previously acquired skills does not generally occur; however, some clinical manifestations (particularly seizures) that appear later in childhood may significantly affect the overall clinical course [Guerrini et al 2003]. Individuals with the milder forms of polymicrogyria survive into adulthood, while those with the most severe forms may die at a young age as a result of such complications as seizures or pneumonia.