תוצאות פתולוגיה של הסרת שומה ....

היי ד"ר נתנזון, קיבלתי תוצאות פתולוגיה של שומה שהסרתי בכף היד. תוכל להסביר לי בבקשה מה זה אומר ומה המשמעויות? תודה. Note (sub number 1): This is a relatively small (~3.5 mm) symmetrical compound melanocytic lesion on acral skin. The dermal component is composed of medium sized nested, mostly bland melanocytes which seem to be slightly smaller in the deep aspect of the lesion. The junctional/intraepidermal component is composed of medium sized single melanocytes with a clearly visible nucleoli, focally scattered along the junction and above it. On immunostains the lesion is highlighted by SOX10 and Melanoma cocktail. HMB45 is positive mainly in the upper parts of the lesion. PRAME is mostly negative. Conclusion: Given the small lesional diameter, young age of the patient, absence of pleomorphism and the described immunophenotype, special site nevus is favored. The lesion is seen at the margins and a conservative re excision with safe margins is mandatory.