תשובות מפתלוגיה מה זה אומר
דיון מתוך פורום גידולי מוח
שלום זה התשובות של של אחי הגדול בן 34 אני אשמח לדעת קצת על התשובות Low grade glial tumor, favor grade I . The presence of an IDH mutation (characteristic of a grade 2 tumor) should be ruled out. Tumor area is identified, infiltrative, with Oltg2 positive mul . . Description: and delicate vascularity. Mitotic activity is inconspicuous and proliferation index by Ki67 is close to zero: . CD34 is negative except in blood vessels. BRAFy600E, IDHI R132H and P53 are negative. ATRX is retained. In addition: Multiple perivascular corpora amylacea and reactive changes post previous b'opsy are noted n area of epen ymal lke hntn is identified. In conclusion, although it may be compatible with a grade I tumor, an underlying IDH mutation should be molecularly ruled out.