שאלה לגבי ההתאמה בין psa ותוצאתה- mri
דיון מתוך פורום אורולוגיה
האם ככל שהpsa יותר נמוך -או נמוך מ3, וה-pirads v2- הוא עד 3, נמצא בפועל בביופסיה שרוב של המקרים כי אין להם ממצא סרטני,והביופסיה היתה מיותרת. או שאין שום סטטיסטיקה מובנקת קראתי את זה פה, או שלא הבנתי נכון את הדברים. In all, 288 patients were analysed. The median patient age, PSA level, prostate volume and PSA density were 69 years, 7.5 ng/mL, 28.7 mL, and 0.26 ng/mL/mL, respectively. The biopsy results were benign, clinically insignificant, and clinically significant prostate cancer in 129 (45%), 18 (6%) and 141 (49%) patients, respectively. The multivariate analysis revealed that PI-RADS v2 score and PSA density were independent predictors for prostate cancer and clinically significant prostate cancer. When PI-RADS v2 score and PSA density were combined, a PI-RADS v2 score of ≥4 and PSA density ≥0.15 ng/mL/mL, or PI-RADS v2 score of 3 and PSA density of ≥0.30 ng/mL/mL, was associated with the highest clinically significant prostate cancer detection rates (76-97%) on the first biopsy. Of the patients in this group with negative biopsy results, 22% were subsequently diagnosed as prostate cancer. In contrast, a PI-RADS v2 score of ≤3 and PSA density of <0.15 ng/mL/mL yielded no clinically significant prostate cancer and no additional detection of prostate cancer on further biopsies.